Scientists at acib GmbH are exploring a new, environmentally friendly way to transform carboxylic acids – common components in organic matter – into valuable aldehydes and alcohols. These are essential building blocks for numerous products, from medicines to flavors. Traditionally, this conversion relies on chemical methods that can be energy-intensive and produce unwanted byproducts. Our research focuses on using natural catalysts called enzymes. These enzymes can precisely and efficiently convert carboxylic acids under mild conditions and for this, they need a helper molecule. Normally this is unstable NADPH, but now the cheaper and more stable NADH also works.

This innovative approach offers a more sustainable alternative to conventional chemical processes. By using enzymes, we can potentially reduce waste, lower energy consumption, and create cleaner industrial processes. This research not only expands our understanding of how enzymes can be used but also opens doors for developing greener and more efficient ways to produce important chemicals, ultimately contributing to a more sustainable future for industrial biotechnology.