COMET FUNDING PERIOD 2015-2019
acib was funded as a K2 research centre in the framework of FFG COMET funding (Competence Centres for Excellent Technologies) by BMVIT, BMWF, and the provinces of Styria, Vienna, Lower Austria and Tyrol. The COMET programme is carried out via FFG. The strategic objectives of COMET are developing new expertise by initiating and supporting long-term research co-operations between science and industry in top-level research, and establishing and securing the technological leadership of companies. By advancing and bundling existing strengths and by integrating international research expertise Austria is to be strengthened as a research location on the long term.

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COMET AREAS
AREA 1
BIOCATALYSIS AND ENZYME TECHNOLOGY

Medical agents, active ingredients of detergents, cosmetics, color pigments or polymers – all depend on chemical syntheses. Most chemical reactions require a high energy input and ecologically harmful organic solvents. The result of many chemical reactions is a mixture of products from which the desired substance must be separated sophisticatedly. About 90 % of all chemical processes are carried out using a type of catalysis. Here, biocatalysis comes into play – as biocatalysts, enzymes transform chemical syntheses into more ecological and economic processes.

READ MORE ABOUT AREA 1

AREA 2
POLYMER- & ENVIRONMENTAL BIOTECHNOLOGY

Polymers are ubiquitous in our world – in clothings, as plastics in cars, in electronic goods, packages and much more. Most polymers and plastics are currently secondary products of the petroleum industry. Dwindling resources and problems with not satisfying recycling methods make it necessary to think of alternatives.

READ MORE ABOUT AREA 2

AREA 3
SYSTEMS BIOLOGY & MICROBIAL CELL ENGINEERING

Microorganisms are essential for many industrial sectors. They are sophisticated factories in micro-format, which are able to perfectly produce pharmaceutical drugs, enzymes for the chemical, pharmaceutical, agrochemical or food industries or a variety of highly valuable chemicals. This requires the use of biotechnological methods. The characterization of production cells is as necessary as cell design, the systematic development of possible production lines or as finding ideal growth conditions which are all major research fields of acib.

READ MORE ABOUT AREA 3

AREA 4
BIOPROSPECTING & SYNTHETIC BIOLOGY

An essential feature of our nature is its enormous biodiversity. Among the countless biomolecules enzymes protrude out yet. As biocatalysts they control all vital processes and solve specific tasks perfectly; similar to highly specialized tools. Microorganisms are specialists, too, and can achieve amazing things through interaction with various cell types. For example certain microbial communities support plants during growth or in the defense of pests.

Using bioprospecting, acib filters out the knowledge about benefits of biological systems that were developed by nature. Based on this, acib researchers define which basic requirements must be met in order to realize a biotechnological process. Finally acib uses new biological systems for environmentally friendly practices.

READ MORE ABOUT AREA 4

AREA 5
BIOPROCESS ENGINEERING

The development of a biotechnological production process is a complex procedure. The establishment of a process in small laboratory scale with a few grams of product is followed by its “upscaling” to an industrial scale of several 100 liters of fermentation medium. “Upscaling” and product purification are not only two of the major challenges of industrial biotechnology but also research priorities at acib.

In the end the industry needs a product of high-purity in order to use it, for example, as a pharmaceutical compound. The result of the fermentation, however, is a mixture of nutrients, microorganisms and hundreds of substances produced in the fermentation. The desired product must be isolated from all other substances.

READ MORE ABOUT AREA 5

AREA 6
ANIMAL CELL TECHNOLOGY & ENGINEERING

Compared to other pharmaceuticals, therapeutic proteins saw an incredible growth rate over the last years. The scientific community and also industry still experience a great enthusiasm and an atmosphere of “gold rush” and innovation. Nevertheless, the development of both cell lines and processes is still mostly based on empirical trial and error methods. The mechanistic details of how a cell is able to handle high production rates of a foreign protein have not received the same attention and optimization within industry.

Therapeutic proteins are mostly produced in Chinese hamster ovary cells, as these CHO cells are able to synthesize proteins similar to those in humans.

READ MORE ABOUT AREA 6

COMET AREAS

AREA 1
BIOCATALYSIS AND ENZYME TECHNOLOGY

Medical agents, active ingredients of detergents, cosmetics, color pigments or polymers – all depend on chemical syntheses. Most chemical reactions require a high energy input and ecologically harmful organic solvents. The result of many chemical reactions is a mixture of products from which the desired substance must be separated sophisticatedly. About 90 % of all chemical processes are carried out using a type of catalysis. Here, biocatalysis comes into play – as biocatalysts, enzymes transform chemical syntheses into more ecological and economic processes.

READ MORE ABOUT THE SCIENTIFIC GOALS & CONTACT

AREA 2
POLYMER- & ENVIRONMENTAL BIOTECHNOLOGY

Polymers are ubiquitous in our world – in clothings, as plastics in cars, in electronic goods, packages and much more. Most polymers and plastics are currently secondary products of the petroleum industry. Dwindling resources and problems with not satisfying recycling methods make it necessary to think of alternatives.

READ MORE ABOUT THE SCIENTIFIC GOALS & CONTACT

AREA 3
SYSTEMS BIOLOGY & MICROBIAL CELL ENGINEERING

Microorganisms are essential for many industrial sectors. They are sophisticated factories in micro-format, which are able to perfectly produce pharmaceutical drugs, enzymes for the chemical, pharmaceutical, agrochemical or food industries or a variety of highly valuable chemicals. This requires the use of biotechnological methods. The characterization of production cells is as necessary as cell design, the systematic development of possible production lines or as finding ideal growth conditions which are all major research fields of acib.

READ MORE ABOUT THE SCIENTIFIC GOALS & CONTACT

AREA 4
BIOPROSPECTING & SYNTHETIC BIOLOGY

An essential feature of our nature is its enormous biodiversity. Among the countless biomolecules enzymes protrude out yet. As biocatalysts they control all vital processes and solve specific tasks perfectly; similar to highly specialized tools. Microorganisms are specialists, too, and can achieve amazing things through interaction with various cell types. For example certain microbial communities support plants during growth or in the defense of pests.

Using bioprospecting, acib filters out the knowledge about benefits of biological systems that were developed by nature. Based on this, acib researchers define which basic requirements must be met in order to realize a biotechnological process. Finally acib uses new biological systems for environmentally friendly practices.

READ MORE ABOUT THE SCIENTIFIC GOALS & CONTACT

AREA 5
BIOPROZESS ENGINEERING

The development of a biotechnological production process is a complex procedure. The establishment of a process in small laboratory scale with a few grams of product is followed by its “upscaling” to an industrial scale of several 100 liters of fermentation medium. “Upscaling” and product purification are not only two of the major challenges of industrial biotechnology but also research priorities at acib.

In the end the industry needs a product of high-purity in order to use it, for example, as a pharmaceutical compound. The result of the fermentation, however, is a mixture of nutrients, microorganisms and hundreds of substances produced in the fermentation. The desired product must be isolated from all other substances.

READ MORE ABOUT THE SCIENTIFIC GOALS & CONTACT

AREA 6
ANIMAL CELL TECHNOLOGY & ENGINEERING

Compared to other pharmaceuticals, therapeutic proteins saw an incredible growth rate over the last years. The scientific community and also industry still experience a great enthusiasm and an atmosphere of “gold rush” and innovation. Nevertheless, the development of both cell lines and processes is still mostly based on empirical trial and error methods. The mechanistic details of how a cell is able to handle high production rates of a foreign protein have not received the same attention and optimization within industry.

Therapeutic proteins are mostly produced in Chinese hamster ovary cells, as these CHO cells are able to synthesize proteins similar to those in humans.

READ MORE ABOUT THE SCIENTIFIC GOALS

AREA LEADERS
AREA 1
BIOCATALYSIS AND ENZYME TECHNOLOGY

Medical agents, active ingredients of detergents, cosmetics, color pigments or polymers – all depend on chemical syntheses. Most chemical reactions require a high energy input and ecologically harmful organic solvents. The result of many chemical reactions is a mixture of products from which the desired substance must be separated sophisticatedly. About 90 % of all chemical processes are carried out using a type of catalysis. Here, biocatalysis comes into play – as biocatalysts, enzymes transform chemical syntheses into more ecological and economic processes.

READ MORE ABOUT THE SCIENTIFIC GOALS & CONTACT

AREA 2
POLYMER- & ENVIRONMENTAL BIOTECHNOLOGY

Polymers are ubiquitous in our world – in clothings, as plastics in cars, in electronic goods, packages and much more. Most polymers and plastics are currently secondary products of the petroleum industry. Dwindling resources and problems with not satisfying recycling methods make it necessary to think of alternatives.

READ MORE ABOUT THE SCIENTIFIC GOALS & CONTACT

AREA 3
SYSTEMS BIOLOGY & MICROBIAL CELL ENGINEERING

Microorganisms are essential for many industrial sectors. They are sophisticated factories in micro-format, which are able to perfectly produce pharmaceutical drugs, enzymes for the chemical, pharmaceutical, agrochemical or food industries or a variety of highly valuable chemicals. This requires the use of biotechnological methods. The characterization of production cells is as necessary as cell design, the systematic development of possible production lines or as finding ideal growth conditions which are all major research fields of acib.

READ MORE ABOUT THE SCIENTIFIC GOALS & CONTACT

AREA 4
BIOPROSPECTING & SYNTHETIC BIOLOGY

An essential feature of our nature is its enormous biodiversity. Among the countless biomolecules enzymes protrude out yet. As biocatalysts they control all vital processes and solve specific tasks perfectly; similar to highly specialized tools. Microorganisms are specialists, too, and can achieve amazing things through interaction with various cell types. For example certain microbial communities support plants during growth or in the defense of pests.

Using bioprospecting, acib filters out the knowledge about benefits of biological systems that were developed by nature. Based on this, acib researchers define which basic requirements must be met in order to realize a biotechnological process. Finally acib uses new biological systems for environmentally friendly practices.

READ MORE ABOUT THE SCIENTIFIC GOALS & CONTACT

AREA 5
BIOPROZESS ENGINEERING

The development of a biotechnological production process is a complex procedure. The establishment of a process in small laboratory scale with a few grams of product is followed by its “upscaling” to an industrial scale of several 100 liters of fermentation medium. “Upscaling” and product purification are not only two of the major challenges of industrial biotechnology but also research priorities at acib.

In the end the industry needs a product of high-purity in order to use it, for example, as a pharmaceutical compound. The result of the fermentation, however, is a mixture of nutrients, microorganisms and hundreds of substances produced in the fermentation. The desired product must be isolated from all other substances.

READ MORE ABOUT THE SCIENTIFIC GOALS & CONTACT

AREA 6
ANIMAL CELL TECHNOLOGY & ENGINEERING

Compared to other pharmaceuticals, therapeutic proteins saw an incredible growth rate over the last years. The scientific community and also industry still experience a great enthusiasm and an atmosphere of “gold rush” and innovation. Nevertheless, the development of both cell lines and processes is still mostly based on empirical trial and error methods. The mechanistic details of how a cell is able to handle high production rates of a foreign protein have not received the same attention and optimization within industry.

Therapeutic proteins are mostly produced in Chinese hamster ovary cells, as these CHO cells are able to synthesize proteins similar to those in humans.

READ MORE ABOUT THE SCIENTIFIC GOALS

COMET FUNDING / 2015-2019
BMVIT

BMDW

FFG

Land Steiermark

Land Niederösterreich

SFG

Standortagentur Tirol

vienna business agency

Komet


COMET ACADEMIC PARTNERS
Boku

AIT

CeBiTec

TUHH

EMBL

MedUni

FH Campus Wien

Resow University of Technology

RCPE

TU Graz

TU Wien

Universitat Barcelona

Universität Wien

Universität Ljubljana

Uni Graz

Universität Pavia

Uni Innsbruck

Tsing Hua University

University of Canterbury


COMET COMPANY PARTNERS
 
3M օsterreich GmbH
AB Enzymes GmbH
ABiTeP GmbH
Agrana Research and Innovation Centre (ARIC)
ARAconsult GmbH
Repligen GmbH
BASF SE
Shire Ltd. (former Baxalta)
bio-ferm Biotechnologische Entwicklung und Produktion GmbH
BIOCRATES Life Sciences AG
BIOMIN Holding GmbH
Biotenzz Gesellschaft füŸr Biotechnologie mbH
Bisolbi-Inter LLC
Bisy e.U.
Boehringer Ingelheim RCV GmbH & Co KG
Carbios SA
Clariant Produkte (Deutschland) GmbH (former SŸüd-Chemie AG)
CNA Diagnostics
DSM Chem Tech R&D BV
Patheon Austria GmbH & Co KG
Evonik Creavis GmbH (former Evonik Industries AG)
G.L. Pharma GmbH
GALAB Laboratories GmbH
Glanzstoff Industries GmbH
HocusLocus GmbH
Qualizyme Diagnostics GmbH (ehem. InFact GesbR)
IPUS GmbH
Jungbunzlauer Austria AG
KWS SAAT AG
Lactosan GmbH & Co KG
Legero Schuhfabrik GmbH
Lonza AG
Microinnova Engineering GmbH
Pfeifer & Langen GmbH & Co. KG
Pyroscience GmbH
RMB Research GmbH
Roal Oy Ltd.
roombiotic GmbH
Sandoz GmbH
Solution Shop AG
Syconium Lactic Acid GmbH
Synapse B.V.
Synovo GmbH
Themis Bioscience GmbH
voestalpine Stahl GmbH
VTU Technology GmbH
ACSI SA
BDI - BioLife Science GmbH
Clariant India Ltd.
GE Healthcare Bio-Sciences AB
PharmaZell GmbH
SŸüdzucker AG
Sanofi-Aventis Deutschland GmbH