In the past years the advent of microbiome research was facilitated by a tremendous decrease in DNA sequencing costs. The progression of sequencing technology and the growing demand for large datasets (beyond the size of the human genome) enabled this favorable progress, which even surpassed Moore’s Law. There are various technologies that benefited from these developments and many of them have a set position in modern laboratories.

Although we live in a world that is more developed than ever, toxins are omnipresent in our environment. During evolution, the human bodies developed ways to cope with many harmful compounds; most of them are degraded enzymatically. A project at the Austrian Centre of Industrial Biotechnology (acib) revealed new insights into life saving processes – especially into the enzymatic detoxification by a special class of enzymes called flavin containing monooxygenases (FMO).

Infections in wounds concern about 2% of the population in developed countries at least once in their lifetime. These kinds of infections can lead to serious complications such as sepsis and need to be diagnosed as fast as possible. But how to find out in a fast way, if a wound is infected?

In our days, enzymes are highly important vehicles that are used to synthesize valuable chemical compounds. However, the optimization of enzymes, a key discipline in industrial biotechnology, struggles because of natural limitations. A new approach to overcome those restrictions is the high-level production of synthetic proteins containing non-canonical amino acids as performed in the Austrian Centre of Industrial Biotechnology.