Although we live in a world that is more developed than ever, toxins are omnipresent in our environment. During evolution, the human bodies developed ways to cope with many harmful compounds; most of them are degraded enzymatically. A project at the Austrian Centre of Industrial Biotechnology (acib) revealed new insights into life saving processes – especially into the enzymatic detoxification by a special class of enzymes called flavin containing monooxygenases (FMO).

In our days, enzymes are highly important vehicles that are used to synthesize valuable chemical compounds. However, the optimization of enzymes, a key discipline in industrial biotechnology, struggles because of natural limitations. A new approach to overcome those restrictions is the high-level production of synthetic proteins containing non-canonical amino acids as performed in the Austrian Centre of Industrial Biotechnology.

Flavors and fragrances are constant companions in our daily life. We find them in food and in cosmetics, and of course, the demand for natural ingredients instead of chemicals is increasing. A special group of enzymes allows us to produce these valuable compounds from raw materials.