Microorganisms play a crucial role for the health and well-being of higher organisms. Host-specific microbial communities of varying complexity form the so-called microbiota. It can consist of several thousand microbial species and includes bacteria, archaea and fungi. These microorganisms exchange a plethora of metabolites with their hosts and can modulate their functioning. Such interactions equally affect humans, animals and plants. This provides us with novel strategies to counteract various diseases and increase the resistance of higher organisms towards abiotic and biotic stresses by modulating the microbiota.
Meat is very fastidious and resource-demanding in its production, still the wastage of spoiled meat products is enormous. Nowadays, a plethora of preservation techniques is available, but many of them cannot fulfill consumer’s demands or are not implementable for industrial production. We evaluated a novel method that is based on bacterial metabolites, which are produced by highly competitive microorganisms that colonize plants and protect them from pathogens. The conducted analyses lead to the conclusion that the microbial load in certain meat products can be significantly reduced by applying nature-based diazine derivatives that are typical metabolites of such beneficial bacteria.
The contamination of chicken eggs with fipronil led to a Europe-wide outcry in 2017. Although this specific case was not in compliance with current regulations, other treatments of hatching eggs with hazardous substances are still common. Contaminations of the eggshells with potentially animal-pathogenic microorganisms require fumigation with toxic chemicals for efficient breeding. Researchers evaluated an alternative decontamination method that is based on bacterial metabolites and showed that it is as efficient as conventional methods.
Beneficial microorganisms present a promising alternative to conventional plant protection and could replace chemical pesticides in the near future. Plant pathogens are responsible for various devastating plant diseases and lead to huge yield losses caused by pre- and postharvest spoilage.
In the past years the advent of microbiome research was facilitated by a tremendous decrease in DNA sequencing costs. The progression of sequencing technology and the growing demand for large datasets (beyond the size of the human genome) enabled this favorable progress, which even surpassed Moore’s Law. There are various technologies that benefited from these developments and many of them have a set position in modern laboratories.