Publikationsgalerie (Englisch)
Low-cost food-grade alternatives for serum albumins in FBS-free cell culture media
The development of cost-effective, serum-free cell culture media is critical for the advancement of cultivated meat production and the biopharmaceutical industry.
Engineering of Transmembrane Alkane Monooxygenases to Improve a Key Reaction Step in the Synthesis of Polymer Precursor Tulipalin A.
The biocatalytic synthesis of valuable chemicals offers a sustainable alternative to conventional chemical routes. This work focuses on improving a critical hydroxylation step in the synthesis of Tulipalin A, a small lactone with an exo-olefin group, that has significant potential as a polymer precursor.
Advancing Genetic Engineering in Methanothermobacter marburgensis for Industrial Biotechnology
First markerless mutagenesis system established, clarifying isoleucine biosynthesis and enabling synthetic pathway integration.
NADH driven enzymatic carboxylic acid reduction
This study delves into the promising realm of NADH-driven enzymatic carboxylic acid reduction, a pivotal transformation in the field of industrial biotechnology.
Biocatalytic Heteroaromatic Amide Formation in Water Enabled by a Catalytic Tetrad and Two Access Tunnel
Green chemistry in action: Our enzyme SpL enables the efficient production of important amide building blocks for drugs directly in water! Faster, cleaner, more sustainable – a breakthrough for industrial biotechnology.
Phosphorylation-condensation cascade reaction for flexible biocatalytic synthesis of C-nucleosides from pentose and nucleobase substrates
Efficient enzyme cascade for C-nucleosides: acib develops a new, highly productive biocatalysis process for the production of pseudouridine 5′-phosphate, a key building block for modern mRNA therapeutics.
Carrier-based immobilization of the Aerococcus viridans L-lactate oxidase
How best to immobilize L-lactate oxidase? Systematic study compares carriers & methods, finding agarose amine supports superior. Key for biosensing/biocatalysis.