Although we live in a world that is more developed than ever, toxins are omnipresent in our environment. During evolution, the human bodies developed ways to cope with many harmful compounds; most of them are degraded enzymatically. A project at the Austrian Centre of Industrial Biotechnology (acib) revealed new insights into life saving processes – especially into the enzymatic detoxification by a special class of enzymes called flavin containing monooxygenases (FMO).
Infections in wounds concern about 2% of the population in developed countries at least once in their lifetime. These kinds of infections can lead to serious complications such as sepsis and need to be diagnosed as fast as possible. But how to find out in a fast way, if a wound is infected?
In our days, enzymes are highly important vehicles that are used to synthesize valuable chemical compounds. However, the optimization of enzymes, a key discipline in industrial biotechnology, struggles because of natural limitations. A new approach to overcome those restrictions is the high-level production of synthetic proteins containing non-canonical amino acids as performed in the Austrian Centre of Industrial Biotechnology.
Flavors and fragrances are constant companions in our daily life. We find them in food and in cosmetics, and of course, the demand for natural ingredients instead of chemicals is increasing. A special group of enzymes allows us to produce these valuable compounds from raw materials.
Welcome to the first of two articles about “Connection Carbon“.
Carbon-carbon bonds are the basis for all vital organic molecules, which makes them attractive building blocks for e.g. pharmaceuticals, fragrances, flavors and many others. The key to an efficient and green production thereof are specific enzymes.
Virus like particles are important tools in the medical field for vaccination or drug delivery systems. They mimic the outside structure of a virus but cannot reproduce themselves anymore. The purification thereof is still a challenge, but some techniques are published already.
CHO cells are an important workhorse for the biotechnological production of pharmaceuticals. Inspite of its long tradition in biotechnological application there is still room to improve the stability of cell lines, which is a research topic at acib.
Microorganisms are ubiquitously present, even if we do not notice them. Some of them are pathogenic, but most of them are essential for our well-being and health. Researchers found out that communities of microorganisms are even able to protect plants, which is a crucial step for agriculture.