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ACIB Publications in refereed journals

M. Tengg, H. Stecher, P. Remler, I. Eiteljoerg, H. Schwab, M. Gruber-Khadjawi: Molecular Characterization of the C-Methyltransferase NovO of Streptomyces spheroides, a valuable enzyme for performing Friedel-Crafts alkylation, J MOL CATAL B-ENZYM2012, 84, 2-8 
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C. Wuensch, S. Glueck, J. Gross, M. Schober, K. Faber, M. Komon-Zelazowska: Regioselecive enzymatic carboxylation of phenols and hydroxystyrene derivatives, ORG LETT2012, 14, 1974-1977 
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A. Lyskowski, M. Tengg, G. Steinkellner, H. Schwab, M. Gruber-Khadjawi: Crystallisation of the novel S-adenosyl-L-methionine dependent C- methyltransferase CouO from Streptomyces rishiriensis and preliminary diffraction data analysis, Acta Crystallogr. Sect. F2012, 68, 451-454 
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B. Wilding, M. Winkler, B. Petschacher, R. Kratzer, A. Glieder, N. Klempier: Nitrile Reductase from Geobacillus kaustophilus: A Potential Catalyst for a New Nitrile Biotransformation Reaction, Adv. Synth. Catal.2012, 354; 2191-2198 
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M. Sauer, D. Mattanovich: Construction of microbial cell factories for industrial bioprocesses, J. Chem. Technol. Biotechnol.2012, 87, 445-450 
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D. Ribitsch, E. Herrero Acero, K. Greimel, A. Dellacher, S. Zitzenbacher, A. Marold, R. Diaz Rodriguez, G. Steinkellner, K. Gruber, H. Schwab, G. Guebitz: A new esterase from Thermobifida halotolerans hydrolyses PET and PLA, Polymers2012, 4, 617-629 
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R. McCoy, C. Jungreuthmayer, F. O’Brian: Influence of flow rate and scaffold pore size on cell behavior during mechanical stimulation in a flow perfusion bioreactor, Biotechnol. Bioeng.2012; http://onlinelibrary.wiley.com/doi/10.1002/bit.24424/abstract 
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F. Mutti, C. Fuchs, D. Pressnitz, N. Turrini, J. Sattler, A. Lerchner, A. Skerra, W. Kroutil: Amination of Ketones by Employing Two New (S)-Selective omega-Transaminases, Eur. J. Org. Chem.2012, 1003-1007 
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B. Wiltschi: Expressed Protein Modifications: Making Synthetic Proteins, Methods Mol. Biol.2012, Vol 813, Part 2, 211-225 
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F. Krainer, C. Dietzsch, T. Hajek, C. Herwig, O. Spadiut, A. Glieder: Recombinant protein expression in Pichia pastoris strains with an engineered methanol utilization pathway, Microb. Cell Fact.2012, 11, 22 
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S. Hanlon, A. Camattari, S. Abad, A. Glieder, M. Kittelmann, S. Lütz, B. Wirz, M. Winkler: Expression of recombinant human flavin monooxygenase and moclobemide N-oxide synthesis on multi-mg scale, Chem. Commun.2012, 48, 6001-6003 
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R. Simon, B. Grischek, F. Zepeck, A. Steinreiber, W. Kroutil: Regio- and Stereoselective Monoamination of Diketones without Protecting Groups, Angew. Chem.2012, 51, 6713-6716 
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S. Rengachari, G. Bezerra, C. Sturm, L. Riegler, C. Gruber, U. Taschler, A. Boeszoermenyi, R. Zimmermann, K. Gruber, M. Oberer: The structure of monoacylglycerol lipase from Bacillus sp. H257 reveals unexpected conservation of the cap architecture between bacterial and human enzymes, BBA-MOL CELL BIOL L2012, 1821, 1012-1021 
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P. Krempl, J. Mairhofer, G. Striedner, G. Thallinger: A Sequence Comparison and Gene Expression Data Integration Add-on for the Pathway Tools Software, Bioinformatics2012; http://dx.doi.org/10.1093/bioinformatics/bts431 
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S. Nehring, N. Budisa, B. Wiltschi: Performance analysis of orthogonal pairs designed for an expanded eukaryotic genetic code, PloS ONE2012, 7(4): e31992 
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E. Herrero Acero, D. Ribitsch, R. Diaz Rodriguez, A. Dellacher, S. Zitzenbacher, M. Schroeder, A. Kandelbauer, S. Heumann, M. Murkovic, H. Schwab, G. Guebitz: Two-step enzymatic functionalisation of polyamide with phenolics, J MOL CATAL B-ENZYM2012; http://www.sciencedirect.com/science/article/pii/S1381117712000781 
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M. Winkler: Organ function in shake flasks: Recombinant human Enzymes for the pharmaceutical Industry, TUGraz Research2012; http://portal.tugraz.at/portal/page/portal/Files/BDR/Oeffentlichkeit/Zeitschriften/research_7_2012.pdf 
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A. Lyskowski, K. Steiner, I. Hajnal, G. Steinkellner, H. Schwab, K. Gruber: Crystallisation of a novel metal-containing cupin from Acidobacterium sp. and preliminary diffraction data analysis, Acta Crystallogr. Sect. F2012, 68, 451-454 
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C. Sygmund, A. Gutmann, I. Krondorfer, M. Kujawa, A. Glieder, B. Pscheidt, D. Haltrich, C. Peterbauer, R. Kittl: Simple and efficient expression of Agaricus meleagris pyranose dehydrogenase in Pichia pastoris, Appl. Microbiol. Biotechnol.2012, 94, 595-704 
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D. Ribitsch, E. Herrero Acero, K. Greimel, I. Eiteljoerg, E. Trotscha, G. Freddi, H. Schwab, G. Guebitz: Characterization of a new cutinase from Thermobifida alba regarding PET-surface hydrolysis, Biocatalysis Biotransformation2012, 30, 2-9 
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R. Kittl, K. Mueangtoom, C. Gonau, S. Khazaneh, C. Sygmund, D. Haltrich, R. Ludwig: A chloride tolerant laccase from the plant ascomycete Botrytis acalda expressed at high levels in Pichia pastoris, J. Biotechnol.2012, 157, 304-314 
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D. Ribitsch, S. Heumann, W. Karl, J. Gerlach, R. Leber, R. Birner – Grünberger, K. Gruber, I. Eiteljoerg, P. Remler, P. Siegert, J. Lange, K. Maurer, G. Berg, G. Guebitz, H. Schwab: Extracellular serine proteases from Stenotrophomonas maltophilia: screening, isolation and heterologous expression in E.coli, J. Biotechnol.2012, 157(1), 140-147 
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B. Grün, T. Scharl, F. Leisch: Modelling time course gene expression data with finite mixtures of linear additive models, Bioinformatics2012, 28, 222-228 
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I. Bednar, R. Tscheliessnig, E. Berger, A. Podgornik, A. Jungbauer: Surface energies of hydrophobic interaction chromatography media by inverse liquid chromatography, J. Chromatogr.2012, 1220, 115-121 
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A. Braun, B. Halwachs, M. Geier, K. Weinhandl, M. Guggemos, J. Marienhagen, A. Ruff, U. Schwaneberg, V. Rabin, D. Torres Pazmino, G. Thallinger, A. Glieder: MuteinDB: The mutein database linking substrates, products and enzymatic reactions directly with genetic variants of enzymes, DATABASE2012, :bas028 
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N. Borth: How the Chinese Hamster might save your life, European Science and Technology2012, 15, 218-219 
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C. Jungreuthmayer, G. Birnbaumer, P. Ertl: Improving the measurement sensitivity of interdigital dielectric capacitors (IDC) by optimizing the dielectric property of the homogeneous passivation layer, Sensors Actuators B: Chem.2012, 162, 418-424 
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C. Jungreuthmayer, J. Zanghellini: Designing optimal cell factories: Integer programing couples elementary mode analysis with regulation, BMC SYST BIOL2012, 6, 103 
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K. Steiner, H. Schwab: Recent advances in rational approaches for enzyme engineering, Computational and Structural Biology Journal2012, online: http://dx.doi.org/10.5936/csbj.201209010

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Publications in Non-Refereed Journals

E. Herrero Acero, D. Ribitsch, A. Marold, K. Greimel, L. Espino Tenorio de Rammer, I. Druzhinina, C. Kubicek, G. Gübitz: Hydrophobins can enhance polyesterase activity on PET, New Biotechnol.2012, 29 (S), 
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S. Weiß, D. Reinsberger, A. Zankel, M. Cardinale, R. Birner – Grünberger, M. Lebhuhn, W. Somitsch, B. Überbacher, G. Gübitz: – Clinoptilolite – a probiotic natural mineral for eupeptic biogas production plants, New Biotechnol.2012, 29(S), 45 
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C. Jungreuthmayer, J. Zanghellini: Designing The Optimal Producer: Integer Programing Combines Elementary Modes With Regulation, New Biotechnol.2012, 29(S), 88 
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M. Felber, M. Buchetics, B. Gasser, D. Mattanovich, H. Pichler: Pichia pastoris as a cell factory – Examining the secretory capabilities , New Biotechnol.2012, 29(S), 92 
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K. Marisch, M. Schoenlieb, D. Scheps, S. Malca, G. Striedner: Expression of cytochrome P450 in Escherichia coli fed-batch cultivations, New Biotechnol.2012, 29(S), 102 
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A. Marold, A. Dellacher, E. Herrero Acero, H. Schwab, G. Gübitz, D. Ribitsch: Surface-directed mutagenesis of cutinases demonstrate the importance of sorption in PET hydrolysis, New Biotechnol.2012, 29(S), 203 
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S. Schindler, M. Sponring, T. Zoegg, M. Koll, H. Brandstetter, R. Schneider, B. Auer: Sructure and function of swine fever virus N-terminal autoprotease, New Biotechnol.2012, 29(S), 212 
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A. Glieder: Industrial Research in Academic Environment, New Biotechnol.2012, 29(2), 235 
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C. Jungreuthmayer, D. Ruckerbauer, J. Zanghellini: How to design an optimal production host, New Biotechnol.2012, 29(S), 235 
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W. Kroutil, K. Faber, D. Clay, M. Hall, G. Tásnádi, C. Winkler, K. Tauber, C. Fuchs: Surfing the ω-transaminase and ene reductase wave: Biocatalytic asymmetric transformations for preparative organic synthesis, New Biotechnol.2012, 29(S), 236 
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M. Winkler, A. Camattari: Recombinant Human Flavin Monooxygenases: Expression and Moclobemide N-oxide Synthesis on Semi-Preparative Scale, New Biotechnol.2012, 29(S), 236 
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E. Herrero Acero, K. Greimel, A. Marold, I. Druzhinina, C. Kubicek, G. Gübitz, D. Ribitsch: Enzymes go big: functionalization of natural and synthetic polymers, New Biotechnol.2012, 29(S), 237 
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K. Greimel, V. Perz, E. Herrero Acero, G. Guebitz: Banning heavy metals from plants: Enzymatic hardening of alkyd resins, New Biotechnol.2012, 29(S), 238 
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D. Mattanovich: Engineering by Design: Systems Biology based Development of Biotechnological Production Strains, New Biotechnol.2012, 29(S), 239 
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L. Fliedl, J. Pontiller, S. Dunzinger, P. Jennings, M. Wieser, J. Grillari, R. Grillari: Human kidney epithelial cell lines in biology and medicine, New Biotechnol.2012, 29(S), 239 
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H. Schwab: Mating design and evolution for powerful protein/enzyme engineering, New Biotechnol.2012, 29(S), 240 
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B. Auer, R. Schneider, T. Heel, M. Koll, S. Schindler, T. Zoegg, H. Brandstetter, M. Sponring: Npro autoprotease fusion technology (NAFT), a platform for industrial peptide/protein production in E. coli, New Biotechnol.2012, 29(S), 240 
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A. Jungbauer: Bioprocess engineering of recombinant proteins: From µl to m³ scale and from batch to continuous, New Biotechnol.2012, 29(S), 240 
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G. Striedner, M. Luchner, R. Gutmann, K. Bayer: Advanced bioprocess monitoring key to process and systems understanding, New Biotechnol.2012, 29(S), 241 
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A. Glieder: Next generation biocatalyst discovery, New Biotechnol.2012, 29(S), 12 
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K. Faber, C. Wuensch, S. Glueck, J. Gross, G. Steinkellner, K. Gruber: Biocatalytix Carboxylation, CHEM LISTY2012, 106, 705 
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ACIB Book Contributions

C. Gruber, J. Pleiss: Molecular modelling of lipase bindng to a substrate-water interface, in: Lipases and Phospholipases: Methods and Applications2012, Sandoval Georgina, Ed.; Springer Protocols-Methods in Molecular Biology, pp861

M. Gruber-Khadjawi: Enzymatic Friedel-Crafts Alkylation catalyzed by S-Adenosyl-L-methionine dependent Methyltransferase, in: Practical Methods for Biocatalysis and Biotransformations2012, J. Withall, P. W. Sutton, Eds., Wiley, Chichester, 2nd Ed., pp:263-267

M. Winkler, A. Glieder, K. Steiner: Hydroxynitrile Lyases: from Nature to Application, Comprehensive Chirality, 2012, 7, Synthetic Methods VI – Enzymatic and Semi Enzymatic, N. Turner, ed. 350-371

 

Associated publications in refereed journals

A. Mellitzer, A. Glieder, R. Weis, C. Reisinger, K. Flicker: Sensitive high-throughput screening for the detection of reducing sugars, Biotechnol. J.2012, 7, 155-162 
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C. Souza, T. Schwabe, H. Pichler, B. Ploier, E. Leitner, H. Schröder, X. Guan, M. Wenk, I. Riezmann, H. Riezmann: A stable yeast strain efficiently producing cholesterol instead of ergosterol is functional for tryptophan uptake, but not weak organic acid resistance, Metab. Eng.2012, 13(5), 555-569 
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H. Thaisuchat, M. Baumann, J. Pontiller, F. Hesse, W. Ernst: Identification of a novel temperature sensitive promoter in cho cells, BMC BIOTECHNOL2012, 11, 51 
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L. Näätsaari, B. Mistlberger, C. Ruth, T. Hajek, F. Hartner, A. Glieder: Deletion of the Pichia pastoris KU70 Homologue Facilitates Platform Strain Generation for Gene Expression and Synthetic Biology, PloS ONE2012, 7(6):e39720 
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E. Christen, R. Gübeli, B. Kaufmann, R. Schoenmakers, N. Budisa, M. Fussenegger, W. Weber, B. Wiltschi, L. Merkel: Evaluation of bicinchoninic acid as a ligand for copper(i)-catalyzed azide-alkyne bioconjugations, ORG BIOMOL CHEM2012; http://dx.doi.org/10.1039/c2ob25556a 
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C. Chitraju, M. Trotzmüller, J. Hartler, H. Wolinski, G. Thallinger, A. Lass, R. Zechner, R. Zimmermann, H. Köfeler, F. Spener: Lipidomic analysis of lipid droplets from murine hepatocytes reveals distinct signatures for nutritional stress, J. Lipid Res.2012, 53, 2142-2152 
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Associated publications in non-refereed journals

K. Greimel, M. Murkovic: Comparison of a PCr based method and a hPLC based method for determination of the soy content of animal feed, Ernährung/Nutrition2012, 36, 245-251 

Associated book contributions

M. Gruber-Khadjawi, M. Fechter, H. Griengl: Cleavage and Formation of Cyanohydrin, in: Enzyme Catalysis in Organic Synthesis, 2012, K. Drauz, H. Gröger, O. May, Eds., 3rd Ed., Vol. II, 2012, pp. 947-990.

 

acib impressions
Rotovapor
Dunkle Kulturen 2
Dunkle Kulturen 1
Strain Collection
Bioreactor IFA Tulln
microorganisms on plate
Labs Wien 1
Synthetic Biology 1