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ACIB publications

Klimacek M., Nidetzky B. From alcohol dehydrogenase to a “one-way” carbonyl reductase by active-site redesign – A mechanistic study of mannitol 2-dehydrogenase from Psedomonas fluorescens. , 2010, 285, 30644-30653

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Fesko K., Uhl M., Steinreiber J., Gruber K., Griengl H. Biocatalytic access to α,α-dialkyl-α-amino acids by a mechanism based approach. Angew. Chem., Int. Ed., 2010, 49, 121-124 (http://dx.doi.org/10.1002/anie.200904395)

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Seisser B., Zinkl R., Gruber K., Kaufmann F., Hafner A., Kroutil W. Cutting long syntheses short: Access to non-natural tyrosine derivatives employing an engineered tyrosine phenol lyase. Adv. Synth. Catal., 2010, 352, 731-736

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Schreiner U., Steinkellner G., Rozzell D., Glieder A, Winkler M. Improved fitness of Arabidopsis thaliana Nitrilase 2. ChemCatChem, 2010, 2, 263-267

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Schreiner U., Hecher B., Obrowsky S., Waich K., Klempier N., Steinkellner G., Gruber K., Rozzell D. J., Glieder A. Winkler M. Directed evolution of Alcaligenes faecalis nitrilase. Enzyme and Microbial Technology, 2010, 47, 140-146

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Abad S., Nahalka J., Bergler G., Speight R., Nidetzky B., Glieder A. Stepwise engineering of a Pichia pastoris D-amino oxidase whole cell catalyst. Microbial Cell Factories, 2010, 9, 24-36

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Karabec M., Lyskowski A., Tauber K. C., Steinkellner G., Kroutil W., Grogan G., Gruber K. Structural insights into substrate specificity and solvent tolerance in alcohol dehydrogenase ADH-‘A’ from Rhodococcus ruber DSM 44541. Chem. Commun., 2010, 46, 6314-6316

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Ribitsch D., Winkler S., Gruber K., Karl W., Wehrschütz-Sigl E., Eiteljörg I., Schratl P., Remler P., Stehr R., Bessler C., Mußmann N., Sauter K., Maurer K.-H., Schwab H. Engineering of choline oxidase from Arthrobacter nicotinae for potential use as biological bleach in detergents. Appl. Microbiol. Biotechnol., 2010, 87, 1743

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Freigassner M., Pichler H., Glieder A. Tuning microbial hosts for membrane protein production. Microbial Cell Factories, 2009, 8, 69

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Ribitsch D., Karl  W., Birner-Gruenberger R, Gruber K., Eiteljoerg I., Remler P., Wieland S.,Siegert P., Maurer KH., Schwab H. C-terminal truncation of a metagenome-derived detergent protease for effective expression in E.coli. J. Biotechnol., 2010, 150, 408-416

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Abad S., Nahalka J., Winkler M., Bergler G., Speight R., Glieder A, Nidetzky B. High level expression of Rhodotorula gracilis D-amino acid oxidase in Pichia pastoris. Biotechnol. Lett., online first

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Dürauer A., Ahrer K., Kaar W., Achmüller C., Sprinzl W., Mayer S., Auer B., Jungbauer A., Hahn R. Npro Autoprotease fusion technology: development, characteristics, and influential factors, Separation Science and Technology, 2010, 45, 2194-2209

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Schmoeger E., Wellhöfer M., Dürauer A, Jungbauer A., Hahn R. Matrix-assisted refolding of autoproease fusion proteins on an ion exchange column: A kinetic investigation, J. Chromatog. A. 2010, 5950-5956

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Hahn R., Seifert, M., Greinstetter S.,  Kanatschnig B., Berger E., Kaar W., Jungbauer A. Peptide affinity chromatography media which bind autoprotease fusion proteins under chaotropic condition. J. Chromatogr. A, 2010, 1217 , 6203-6213

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Associated publications

Stadlmayr G., Mecklenbräuker A., Rothmüller M., Maurer M., Sauer M., Mattanovich D., Gasser B. Identification and characterisation of novel Pichia pastoris promotors for heterologous protein production. J. Biotechnol., 2010, 150, 519-529

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Dragosits M., Mattanovich D., Gasser B. Induction and measurement of UPR and osmotic stress in the yeast Pichia pastoris. Method. Enzymol., 2010, 489, 168-188

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Yuryev R., Briechle S., Gruber-Khadjawi M., Griengl H., Liese A. Asymmetric Retro-Henry reaction catalyzed by hydroxynitrile lyase from Hevea brasiliensis. ChemCatChem, 2010, 2, 981-986

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Schmoeger E., Paril C., Tscheliessnig R., Jungbauer A. Adsorption of plasmid DNA on ceramic hydroxyapatite chromatographic materials. J. Sep. Sci., 2010, 33, 3125-3136

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Schmoeger E., Wellhoefer M., Dürauer A., Hahn R. Matrix-assisted refolding of autoprotease fusion proteins on anion exchange column: a kinetic investigation. J. Chromatogr., 2010, 1712, 5950-5956

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Krahulec, S., Petschacher, B., Wallner, M., Longus, K., Klimacek, M., Nidetzky, B. Fermentation of mixed glucose-xylose substrates by engineered strains of Saccharomyces cerevisiae: role of the coenzyme specificity of xylose reductase, and effect of glucose on xylose utilization. Microbial Cell Factories, 2010, 9, 16

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Keidel E.-M., Ribitsch D., Lottspeich F. Equalizer Technology: Mode of Action. Proteomics, 2010, 10, 2089-2098

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Koszelewski D., Tauber K., Faber K., Kroutil W.ω-Transaminases for the synthesis of non-racemic α-chiral amines. Trends Biotechnol., 2010, 28, 324-332

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Clay, D., Koszelewski D., Grischek B., Lavandera I., Kroutil W. Testing of microrganisms for ω-transaminase activity. Tetrahedron, 2010, 21, 2001-2009

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Torres Pazmino,D. E., Winkler M., Glieder A., Fraaije M. W. Monooxygenases as biocatalysts – classification, mechanistic aspects and biotechnological applications. J. Biotechnol., 2010, 146, 9-24

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Klimacek M., Krahulec S., Sauer U., Nidetzky B. Limitations in xylose-fermenting Saccharomyces cerevisiae made evident through comprehensive metabolite profiling and thermodynamic analysis. Appl. Environm. Microbiol. 2010, 76, 7566-7574

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Luley-Goedl C., Nidetzky B. Carbohydrate synthesis by disaccharide phosphorylases: reactions, catalytic mechanisms and applications in the glycosciences. Biotechnol. J. 2010, 5, 1324-1338

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Yuryev, R., Purkarthofer, T., Gruber, M., Griengl, H., Liese A. Kinetic studies of asymmetric Henry reaction catalyzed by hydroxynitrile lyase from Hevea brasiliensis. Biocatal. Biotransform. 2010, 28, 348-356.

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Safina G., Ludwig R, Gorton L. A simple and sensitive method for lactose detection based on direct electron transfer between immobilised cellobiose dehydrgenase and screen-printed carbon electrodes. Electrochim. Acta, 2010, 55, 7690-7695

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Strain Collection
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Bioreactor IFA Tulln
Fermenter Monitoring
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Dunkle Kulturen 2
Dunkle Kulturen 1