ACIB publications

Klimacek M., Nidetzky B. From alcohol dehydrogenase to a “one-way” carbonyl reductase by active-site redesign - A mechanistic study of mannitol 2-dehydrogenase from Psedomonas fluorescens. , 2010, 285, 30644-30653

 

Fesko K., Uhl M., Steinreiber J., Gruber K., Griengl H. Biocatalytic access to α,α-dialkyl-α-amino acids by a mechanism based approach. Angew. Chem., Int. Ed., 2010, 49, 121-124 (http://dx.doi.org/10.1002/anie.200904395)

 

Seisser B., Zinkl R., Gruber K., Kaufmann F., Hafner A., Kroutil W. Cutting long syntheses short: Access to non-natural tyrosine derivatives employing an engineered tyrosine phenol lyase. Adv. Synth. Catal., 2010, 352, 731-736

 

Schreiner U., Steinkellner G., Rozzell D., Glieder A, Winkler M. Improved fitness of Arabidopsis thaliana Nitrilase 2. ChemCatChem, 2010, 2, 263-267

 

Schreiner U., Hecher B., Obrowsky S., Waich K., Klempier N., Steinkellner G., Gruber K., Rozzell D. J., Glieder A. Winkler M. Directed evolution of Alcaligenes faecalis nitrilase. Enzyme and Microbial Technology, 2010, 47, 140-146

 

Abad S., Nahalka J., Bergler G., Speight R., Nidetzky B., Glieder A. Stepwise engineering of a Pichia pastoris D-amino oxidase whole cell catalyst. Microbial Cell Factories, 2010, 9, 24-36

 

Karabec M., Lyskowski A., Tauber K. C., Steinkellner G., Kroutil W., Grogan G., Gruber K. Structural insights into substrate specificity and solvent tolerance in alcohol dehydrogenase ADH-‘A’ from Rhodococcus ruber DSM 44541. Chem. Commun., 2010, 46, 6314-6316

 

Ribitsch D., Winkler S., Gruber K., Karl W., Wehrschütz-Sigl E., Eiteljörg I., Schratl P., Remler P., Stehr R., Bessler C., Mußmann N., Sauter K., Maurer K.-H., Schwab H. Engineering of choline oxidase from Arthrobacter nicotinae for potential use as biological bleach in detergents. Appl. Microbiol. Biotechnol., 2010, 87, 1743

 

Freigassner M., Pichler H., Glieder A. Tuning microbial hosts for membrane protein production. Microbial Cell Factories, 2009, 8, 69

 

Ribitsch D., Karl  W., Birner-Gruenberger R, Gruber K., Eiteljoerg I., Remler P., Wieland S.,Siegert P., Maurer KH., Schwab H. C-terminal truncation of a metagenome-derived detergent protease for effective expression in E.coli. J. Biotechnol., 2010, 150, 408-416

 

Abad S., Nahalka J., Winkler M., Bergler G., Speight R., Glieder A, Nidetzky B. High level expression of Rhodotorula gracilis D-amino acid oxidase in Pichia pastoris. Biotechnol. Lett., online first

 

Dürauer A., Ahrer K., Kaar W., Achmüller C., Sprinzl W., Mayer S., Auer B., Jungbauer A., Hahn R. Npro Autoprotease fusion technology: development, characteristics, and influential factors, Separation Science and Technology, 2010, 45, 2194-2209

 

Schmoeger E., Wellhöfer M., Dürauer A, Jungbauer A., Hahn R. Matrix-assisted refolding of autoproease fusion proteins on an ion exchange column: A kinetic investigation, J. Chromatog. A. 2010, 5950-5956

 

Hahn R., Seifert, M., Greinstetter S.,  Kanatschnig B., Berger E., Kaar W., Jungbauer A. Peptide affinity chromatography media which bind autoprotease fusion proteins under chaotropic condition. J. Chromatogr. A, 2010, 1217 , 6203-6213

 

Associated publications

Stadlmayr G., Mecklenbräuker A., Rothmüller M., Maurer M., Sauer M., Mattanovich D., Gasser B. Identification and characterisation of novel Pichia pastoris promotors for heterologous protein production. J. Biotechnol., 2010, 150, 519-529

 

Dragosits M., Mattanovich D., Gasser B. Induction and measurement of UPR and osmotic stress in the yeast Pichia pastoris. Method. Enzymol., 2010, 489, 168-188

 

Yuryev R., Briechle S., Gruber-Khadjawi M., Griengl H., Liese A. Asymmetric Retro-Henry reaction catalyzed by hydroxynitrile lyase from Hevea brasiliensis. ChemCatChem, 2010, 2, 981-986

 

Schmoeger E., Paril C., Tscheliessnig R., Jungbauer A. Adsorption of plasmid DNA on ceramic hydroxyapatite chromatographic materials. J. Sep. Sci., 2010, 33, 3125-3136

 

Schmoeger E., Wellhoefer M., Dürauer A., Hahn R. Matrix-assisted refolding of autoprotease fusion proteins on anion exchange column: a kinetic investigation. J. Chromatogr., 2010, 1712, 5950-5956

 

Krahulec, S., Petschacher, B., Wallner, M., Longus, K., Klimacek, M., Nidetzky, B. Fermentation of mixed glucose-xylose substrates by engineered strains of Saccharomyces cerevisiae: role of the coenzyme specificity of xylose reductase, and effect of glucose on xylose utilization. Microbial Cell Factories, 2010, 9, 16

 

Keidel E.-M., Ribitsch D., Lottspeich F. Equalizer Technology: Mode of Action. Proteomics, 2010, 10, 2089-2098

 

Koszelewski D., Tauber K., Faber K., Kroutil W. ω-Transaminases for the synthesis of non-racemic α-chiral amines. Trends Biotechnol., 2010, 28, 324-332

 

Clay, D., Koszelewski D., Grischek B., Lavandera I., Kroutil W. Testing of microrganisms for ω-transaminase activity. Tetrahedron, 2010, 21, 2001-2009

 

Torres Pazmino,D. E., Winkler M., Glieder A., Fraaije M. W. Monooxygenases as biocatalysts - classification, mechanistic aspects and biotechnological applications. J. Biotechnol., 2010, 146, 9-24

 

Klimacek M., Krahulec S., Sauer U., Nidetzky B. Limitations in xylose-fermenting Saccharomyces cerevisiae made evident through comprehensive metabolite profiling and thermodynamic analysis. Appl. Environm. Microbiol. 2010, 76, 7566-7574

 

Luley-Goedl C., Nidetzky B. Carbohydrate synthesis by disaccharide phosphorylases: reactions, catalytic mechanisms and applications in the glycosciences. Biotechnol. J. 2010, 5, 1324-1338

 

Yuryev, R., Purkarthofer, T., Gruber, M., Griengl, H., Liese A. Kinetic studies of asymmetric Henry reaction catalyzed by hydroxynitrile lyase from Hevea brasiliensis. Biocatal. Biotransform. 2010, 28, 348-356.

 

Safina G., Ludwig R, Gorton L. A simple and sensitive method for lactose detection based on direct electron transfer between immobilised cellobiose dehydrgenase and screen-printed carbon electrodes. Electrochim. Acta, 2010, 55, 7690-7695