An emerging focus for the biotech-industry is to implement “Quality by Design” criteria in their production processes to further optimize economics. According to this concept the quality of a certain product arises from the detailed knowledge about the product itself and of its production process and the risks contained therein. The analysis and improvement of such production processes in order to increase their efficacy and cost-efficiency is the main goal of the research field Bioprocess Engineering.
Biotechnological production processes include the cultivation of the cells, recovery of the product, and process design and -management for the production of chemicals, enzymes, microorganisms and biopharmaceuticals. Currently such processes mostly are conducted batch-wise.An important step towards process intensification is the implementation of continuous processes, also in the field of downstream processing.
The molecular information gained in off-line analyses with the tools of transcriptomics, proteomics and metabolomics is linked to information from on-line monitoring. Advanced data handling and mathematical modelling of this combined information with statistical tools result in more predictable bioprocesses. This is also a basis for further process optimization.
Another focus of the research field Bioprocess Engineering is the development and application of novel materials and unit operations for more efficient bioprocesses
|Key Researcher||Prof. Dr. Alois Jungbauer|
Dr. Concetta Giuliani