Protein Design & Engineering
In nature, proteins evolve to support organisms’ survival and propagation. For utilization outside their original habitat proteins need to be re- or de novo designed and adapted to non-natural conditions and application-specific requirements using protein engineering.
Our team has broad expertise in the fields of molecular enzymology, structural biology and biotechnology. Research activities increase the fundamental knowledge on structure-function relationships of proteins on the molecular level by investigating for example catalytic mechanisms, selectivity and specificity, stability or interactions with other (macro-)molecules.
We apply our expertise to reach new milestones like the design of minimal enzymes or complex enzyme systems. A major challenge is the design and engineering of unprecedented functionalities, which will enable industrial biocatalysis to perform chemical reactions not yet accessible by the current portfolio of biocatalysts.
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Key Researcher |
Prof. Dr. Helmut Schwab |
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| Coordination/Contact |
Dr. Sabine Feichtenhofer |